Abstract: Objective To study the primary tumor type, clinical features and prognosis of orbital metastatic tumors. Design Retrospective case series. Participants 65 patients with orbital metastatic tumors in the Third Medical Center of PLA General Hospital from 2006 to 2017. Methods The clinical records of the participants were reviewed and analyzed. Main Outcome Measures Sex, age, affected eye, primary tumor location. Results Of the 65 patients, 38 were male. The average age at the time of patient visit was 0.6-83 years-old, median 46 years-old. There were 26 cases of right eye, 29 cases of left eye and 10 cases of both eyes (3 from breast cancer, 3 from neuroblastoma, 3 from leukemia and 1 from gastrointestinal tract tumors). The primary sites of orbital metastatic tumors were breast (12 cases), lung (11 cases), leukemia (10 cases), adrenal gland (8 cases), gastrointestinal tract (6 cases), liver (4 cases), kidney (2 cases), thymus (2 cases), bladder, prostate, uterus, joints, lower limbs (1 case each), and 5 cases of unknown origin. The most common primary tumors in adults were breast cancer, lung cancer and gastrointestinal tumors. Conclusion In this study, the age distribution of orbital metastatic tumors is wide. The top three primary tumors in adults are breast cancer, lung cancer and gastrointestinal tumors. （Ophthalmol CHN, 2020, 29: 396-399）

Key words: orbital tumors, metastatic cancer, prognosis