Abstract: Objective To explore the safety and effectiveness of endoscopic cyclophotocoagulation (ECP) in the treatment of post-traumatic refractory glaucoma. Design Retrospective case series. Participants 24 eyes of 24 post-traumatic refractory glaucoma patients who previously had undergone anti-glaucoma surgeries at least 1 time at Beijing Tongren Hospital from May 2013 to May 2020. Methods ECP was used to treat all patients. Patients were followed up for at least 6 months and average 3.6±2.3 years (range 6 months to 7 years). Changes in intraocular pressure (IOP), visual acuity, the number of IOP-lowering drugs and complications were reviewed. The data were analyzed by ANOVA and paired t test. Main Outcome Measures IOP, visual acuity and the number of IOP-lowering drugs. Results The average pre-operation IOP was 37.8±8.7 mmHg. The IOP at last visit (21.9±6.9 mmHg) was significantly lower than that before the ECP (P<0.001), and the IOP was successfully controlled in 83.3%. The number of IOP-lowering drugs used before operation was 2.75±0.79, and it was 0.88±1.12 at the last follow-up after ECP. The difference was statistically significant (P＜0.001). The postoperative visual acuity remained unchanged or improved in 87.5% of the patients. There was no severe complication observed during or after ECP. The average follow-up of 3.6 years showed that ECP was effective in the treatment of traumatic refractory glaucoma. (Ophthalmol CHN, 2021, 30: 142-146)

Key words: traumatic glaucoma, refractory glaucoma, cyclophotocoagulation, endoscope