Abstract: Overnight orthokeratology lenses reshaping the corneal morphology has become one of the important means to correct and delay the progress of myopia. In recent years, the prevalence of teenager’s myopia in China was higher and the demand for orthokeratology is increasing day by day. Corneal complications caused by overnight orthokeratology lenses are not uncommon in clinic. Infectious keratitis, as one of the most serious complications, poses a great threat to children's vision and should be paid great attention to. Identifying the risk factors, emphasizing the standard daily care, and regular follow-up are the keys to prevent the occurrence of orthokeratology lens-related infectious keratitis. Ophthalmologists should strengthen the understanding of early manifestation orthokeratology lens-related infectious keratitis, so as to early diagnosis and reasonable therapy, which contribute to better visual outcome. (Ophthalmol CHN, 2021, 30: 329-332)

Key words: orthokeratology, myopia, infectious keratitis