Abstract:  Objective To evaluate the clinical effect of penetrating keratoplasty (PKP) performed with internationally acquired corneas from donors of a different race. Design Retrospective case series. Participants 10 eyes from 10 patients with corneal leucoma, corneal endothelial dysfunction or corneal graft failure that underwent PKP in Beijing Tongren Eye Center, Beijing Tongren Hospital between October 2002 to March 2003 (10 corneas from Caucasians： 8 eyes，Hispanic：1 eye，African-American：1 eye). Method All cases underwent PKP with corneas from donors of a different race from the Tissue Bank International (TBI), and for whom a mean of 12.6±3.86 months of follow-up was available. Main Outcome Measure Visual acuity, corneal transparency, stromal edema and graft neovascularization. Results Among the 10 eyes that met inclusion criteria, there were 4 eyes graft survival at 1 year. The opacity, edema and neovascularization of the graft wore observed in the other 6 eyes. The overall rate of rejection was 60%. Conclusions This small sample study shows the internationally acquired corneas different race donor corneal tissue can be used for PKP. (Ophthalmol CHN, 2013, 22: 98-100)

Key words: penetrating keratoplasty; , race, graft survival