Ophthalmology in China

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Who touched my optic nerve? -The causative analysis of optic nerve damage in normal tension glaucoma

Ren Zeqin   

  1. Department of Ophthalmology, the People Hospital of Peking University, Beijing 100044, China
  • Received:2020-01-26 Online:2020-03-25 Published:2020-03-25
  • Contact: Ren Zeqin, Email: renzeqin@163.com

Abstract: Normal tension glaucoma (NTG) and high intraocular pressure (IOP) primary open-angle glaucoma (POAG) represent a “continuum”. Based on the pathophysiology, this paper discusses the relationship between IOP and optic nerve damage in NTG, and holds that the papillary lamina cribrosa is the intermediate link of the above relationship and its “continuum” concept, and that the IOP and the lamina cribrosa jointly constitute the initial factors of optic nerve damage in glaucoma. (Ophthalmol CHN, 2020, 29: 87-89)

Key words: normal tension glaucoma/pathophysiology, intraocular pressure, optic nerve, lamina cribrosa