Abstract: Objective To investigate distribution and influencing factors of intraocular pressure in hospital-based myopic teenagers. Design Retrospective case series. Participants  973 myopic teenagers (1946 eyes) were enrolled from the Eye Hospital of Wenzhou Medical University from 2011 to 2013. Methods Objective optometry with auto-refractor (Topcon KR-8800), and subjective optometry with a phoropter (Topcon VT-10) were performed. The intraocular pressure (IOP) was measured by noncontact tonometer (Canon TX-F). All subjects was divided into 5-9 years old, 10-14 years old and 15-18 years old groups. Myopic degree based on spherical equivalent refraction (SE) was divided into mild myopia, moderate myopia and high myopia groups. Main Outcome Measures IOP and SE. Results In 973 myopic teenagers, 432 were male (44.40%). Mean SE of two eyes was (-2.42±1.49) D , and mean IOP of two eyes was (17.43±3.02) mmHg (17.52±3.00 mmHg in right eyes and 17.34±3.04 mmHg in left eyes). 10.48% of the left eyes, 10.38% of the right eyes and 14.29% of either eyes had an IOP >21 mmHg. Female had higher IOPs than male (17.69±2.94 mmHg versus 17.30±3.05 mmHg; t=-1.987, P=0.046). IOP decreased gradually with age (5-9 years old 17.29±3.02 mmHg, 10-14 years old 17.59±2.95 mmHg and 15-18 years old 17.81±3.30 mmHg). There was significant correlation between IOP and SE (r=-0.110, P<0.001). The linear function of IOP (Y) with SE (X) was Y=-0.224X+16.972 (F=11.812, P<0.001). Conclusions IOP of hospital-based myopic teenagers increased with age and myopic degree. The IOP in females was higher than that in males. More than 10% of myopic teenager had an IOP greater than 21 mmHg. (Ophthalmol CHN, 2022, 31: 39-44)

Key words:  intraocular pressure, myopia, teenager