Abstract: Objective To observe the accommodative change in patients with diabetic retinopathy after retinal photocoagulation. Design Prospective case series. Participants 15 patients (30 eyes) treated with retinal photocoagulation for diabetic retinopathy, with average age 57.4±13.4 years. Methods Accommodative indexes and visual acuity of the same eyes of all the patients were measured before treatment and on 1st , 3rd , 7th , 14th day after treatment. Main Outcome Measures Amplitude of accommodation (AA), positive and negative relative accommodation (PRA/NRA), best corrected visual acuity (BCVA), near visual acuity (VA-N). Results The AA and PRA of post-treatment were lower than pre-treatment (all P＜0.05). The post-treatment change happened from the 1st day, reached peak on 3rd day, and partially recovered on 7th day, but could not recovery to the pre-treatment on 14th day. There was no significant difference between pretreatment and post-treatment NRA (P＞0.05). The VA-N of post-pretreatment was lower than pre-treatment (P＜0.05), and the change trend was similar with AA and PRA. There was no significant difference between pretreatment and post-treatment BCVA (P＞0.05). Conclusion In post-treatment 14 days, retinal photocoagulation can cause decline of accommodative amplitude in patients with diabetic retinopathy. （Ophthalmol CHN， 2014, 23： 322-325）

Key words: diabetic retinopathy, retinal photocoagulation, accommodation