国际眼科纵览 ›› 2024, Vol. 48 ›› Issue (2): 145-150.doi: 10.3760/ cma.j.issn.1673-5803.2024.02.012

• 综述 • 上一篇    下一篇

生物陶瓷材料在眼病治疗中的应用

麦唐钦 唐尚漳 熊柯   

  1. 南方医科大学南方医院眼科,广州 510515
  • 收稿日期:2023-10-24 出版日期:2024-04-22 发布日期:2024-04-29
  • 通讯作者: 熊柯,Email:xiongk@smu.edu.cn
  • 基金资助:
    广东省重点区域研发计划项目(2020B090924004)

Application of bioceramics in the treatment of eye diseases

Mai Tangqin, Tang Shangzhang,  Xiong Ke   

  1. Department of Ophthalmology, Nanfang Hospital of Southern Medical University, Guangzhou 510515, China
  • Received:2023-10-24 Online:2024-04-22 Published:2024-04-29
  • Contact: Xiong Ke, Email: xiongk@smu.edu.cn
  • Supported by:
    Key-Area Research and Development Program of Guangdong Province (2020B090924004)

摘要: 生物陶瓷材料相对于金属和聚合物等生物材料,具有良好的生物相容性和理化稳定性,主要用于修复骨骼、牙齿等生物硬组织。目前其在眼科领域也表现出较好的组织相容性和理化稳定性。生物活性玻璃被用于制作人工角膜裙边的材料,羟基磷灰石则常用于眼眶修复。此外羟基磷灰石和β-磷酸三钙也常应用于眼眶骨折后修复和缺陷的修补,氧化铝以及复合材料可用于义眼制作,增加其稳定性。(国际眼科纵览,2024, 48:145-150)

关键词: 生物陶瓷材料;人工角膜;眼眶 

Abstract: Compared with metal, polymer and other biomaterials, bioceramic materials have good biocompatibility and physicochemical stability, and are mainly used to repair biological hard tissues such as bones and teeth. At present, it shows good histocompatibility and physicochemical stability in fields of ophthalmology. Bioactive glass is used to make the skirt of artificial cornea, and hydroxyapatite is often used in orbital repair. In addition, hydroxyapatite and β-tricalcium phosphate (β-TCP) are also commonly used in orbital fracture repair and defect repair. Alumina and composite materials can be used to make artificial eyes to increase their stability.  (Int Rev Ophthalmol, 2024, 48: 145-150)

Key words: bioceramic materials, keratoprosthesis, orbital fracture