国际眼科纵览 ›› 2025, Vol. 49 ›› Issue (1): 13-18.doi: 10.3760/cma.j.cn115500-20240917-01003

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高度近视并发性白内障的术后并发症

张烨 齐姣 竺向佳   

  1. 复旦大学附属眼耳鼻喉科医院眼科 国家卫生健康委近视眼及相关眼病重点实验室 中国医学科学院近视眼及相关眼病重点实验室,上海200031
  • 收稿日期:2024-09-17 出版日期:2025-02-22 发布日期:2025-02-20
  • 通讯作者: 竺向佳,Email:zhuxiangjia1982@126.com
  • 基金资助:
    国家自然科学基金(82122017,82101100)

Postoperative complications of cataracts associated with high myopia

Zhang Ye, Qi Jiao, Zhu Xiangjia   

  1. Department of Ophthalmology, Eye & ENT Hospital, Fudan University; Key Laboratory of Myopia and Related Eye Diseases, NHC; Key Laboratory of Myopia and Related Eye Diseases, Chinese Academy of Medical Sciences, Shanghai 200031, China

  • Received:2024-09-17 Online:2025-02-22 Published:2025-02-20
  • Contact: Zhu Xiangjia, Email: zhuxiangjia1982@126.com
  • Supported by:
    National Natural Science Foundation of China (82122017, 82101100)

摘要: 高度近视并发性白内障作为一种高致盲风险的复杂白内障,其术后并发症风险显著增加,严重威胁高度近视人群视觉健康。常见的并发症包括早期眼压升高、囊袋收缩综合征、后发性白内障及人工晶状体脱位。高度近视眼由于眼轴增长引起的一系列解剖结构异常、眼内微炎症环境、氧化-抗氧化失衡等病理变化,导致房水流出通道结构与动力学异常、晶状体上皮细胞上皮-间质转化、悬韧带松弛等,从而增加了白内障术后并发症的发生风险。临床上,通过术中囊膜抛光、谨慎应用张力环及术后密切监测并早期干预,可在一定程度上降低这些并发症的发生。(国际眼科纵览,2025, 49:13-18)

关键词: 白内障, 高度近视, 术后并发症

Abstract: Highly myopic cataract, as a complex cataract type associated with a high risk of blindness, significantly increases the incidence of postoperative complications, thereby posing a serious threat to the visual health of highly myopic individuals. The common postoperative complications associated with high myopia-related cataracts, include early intraocular pressure elevation, capsular contraction syndrome, posterior capsular opacification, and intraocular lens dislocation. Previous studies have shown that the pathological changes in highly myopic eyes, such as anatomical abnormalities caused by axial elongation, intraocular microinflammatory environments, and oxidative-antioxidative imbalances, contribute to structural and dynamic anomalies in aqueous humor outflow, epithelial-mesenchymal transition of lens epithelial cells, and loosening of the zonular fibers. These factors collectively increase the risk of postoperative complications. Clinically, measures such as meticulous polishing of the capsule during surgery, cautious use of capsular tension rings, and close postoperative monitoring with early intervention can help mitigate these complications to some extent.  (Int Rev Ophthalmol, 2025, 49:  13-18)

Key words: cataract, high myopia, postoperative complications