国际眼科纵览 ›› 2015, Vol. 39 ›› Issue (1): 25-29.doi: 103706/ cma.j.issn.16735803201501005

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眼底自发荧光技术在湿性年龄相关性黄斑变性诊断中的应用

徐晓莉  张喜梅   

  1. 030001 太原,山西医科大学(徐晓莉系在读研究生);030002 太原,山西省眼科医院(张喜梅)
  • 收稿日期:2014-07-14 出版日期:2015-02-22 发布日期:2015-03-03
  • 通讯作者: 张喜梅,Email:ximeizhang@sina.cn E-mail:ximeizhang@sina.cn
  • 基金资助:

    山西省科技攻关项目(20090311063)

Application of fundus autofluorescence in diagnosis of wet agerelated macular degeneration

XU Xiao-li1, ZHANG Xi-mei2   

  1. 1Shanxi Medical University, Taiyuan 030001,China; 2Shanxi Eye Hospital,Taiyuan 030002, China
  • Received:2014-07-14 Online:2015-02-22 Published:2015-03-03
  • Contact: ZHANG Ximei, Email:ximeizhang@sina.cn E-mail:ximeizhang@sina.cn

摘要: 湿性年龄相关性黄斑变性是年龄相关性黄斑变性的晚期阶段,可导致80%以上患者重度视力丧失,目前临床上诊断主要依靠相干光断层扫描和荧光素眼底血管造影等形态学检查手段,而眼底自发荧光(fundus autofluorescence,FAF)成像技术作为一种非侵入性检测手段,能反应脂褐质的分布及视网膜色素上皮层的活性,已逐渐成为湿性年龄相关性黄斑变性诊治中的观测指标之一。

Abstract: Wet agerelated macular degeneration (wAMD), the advanced stage of age-related macular degeneration (AMD), can lead to severe visual loss in more than 80% patients. At present, its diagnosis mainly depends on the morphological examinations, such as optical coherence tomography (OCT)and fundus fluorescein angiography (FFA). As a noninvasive examination, fundus autofluorescence (FAF) imaging has gradually become one of the observable indicators of wAMD, which can reflect the distribution of lipofuscin and the activity of retinal pigment epithelium (RPE).