International Review of Ophthalmology ›› 2021, Vol. 45 ›› Issue (1): 61-66.doi: 10.3760/cma.j.issn.1673-5803.2021.01.012

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Clinical application of macular pigment optical density

Tian Lulu1, Zhou Xiyuan2   

  1. 1Chongqing Medical University, Chongqin 400016, China; 2 Department of Ophthalmology, The Second Affiliated Hospital of Chongqing Medical University, Chongqin 400010, China
  • Received:2020-09-09 Online:2021-02-22 Published:2021-02-22
  • Contact: Zhou Xiyuan, Email: zhouxiyuan2002@aliyun.com E-mail:zhouxiyuan2002@aliyun.com

Abstract: Macular area in the posterior pole of human retina is rich in macular pigments (MP), which have important protective significance to the retina and are closely related to human visual function. MP levels were assessed by macular pigment optical density (MPOD). At present, more and more studies have shown that MP reduction or loss is of great significance for the development and prognosis of a variety of ophthalmic diseases (including age\|related macular degeneration, diabetic retinopathy, glaucoma, etc), and the measurement of MPOD also plays a role in the diagnosis, management and treatment of related systemic diseases (such as Sjogren-Larsson syndrome).

Key words: macular pigment, macular pigment optical density, age-related macular degeneration, diabetic retinopathy