关键词: 复发性视网膜脱离, 增生性玻璃体视网膜病变

Abstract:  Objective To investigate the baseline ocular characteristics of patients with recurrence following vitrectomy for primary rhegmatogenous retinal detachment (RRD) and identify potential risk factors for the recurrence. Design Retrospective case series. Participants 16 patients (16 eyes) with recurrent retinal detachment after initial vitrectomy for RRD at Beijing Hua'er Hospital from January 2017 to December 2021 were selected, and 45 patients (45 eyes) who did not experience recurrence after initial vitrectomy during the same period were randomly selected as the control group. Methods Clinical data and ophthalmic examination results of the patients were analyzed retorspetively. We compared the clinical data at the initial diagnosis (course of disease, lens status, macular involvement, hole location, extent of detachment, inferior involvement, PVR grading, axial length, preoperative visual acuity, preoperative intraocular pressure) between the two groups, and recorded the characteristics in recurrence and follow-up. Logistic regression analysis was used to identify risk factors for recurrent retinal detachment after vitrectomy. Main Outcome Measures Course of disease, lens status, macular involvement, hole location, extent of detachment, inferior involvement, PVR grading. Results Univariate analysis showed that wider extent of retinal detachment (χ2=10.048, P=0.002), poor visual acuity (χ2=10.678, P=0.001), inferior hole location (χ2=5.972, P=0.045), inferior quadrant involvement (χ2=5.054, P=0.025), and PVR≥C grade (χ2=16.775, P<0.001) were associated with recurrence. Logistic regression analysis further indicated that the OR value for PVR grading ≥C (X1) was 8.47 (95% CI: 1.521~47.163, P=0.015). The main effect model for risk factors of recurrent retinal detachment was established as Logit (P)=β0(-3.322)+2.136X1 (χ2=23.133, P<0.001). Conclusion C grade or worse PVR is an important risk factor for recurrence of retinal detachment after vitrectomy for RRD. (Ophthalmol CHN, 2024, 33: 35-38)

Key words: recurrent retinal detachment, proliferative vitreoretinopathy