关键词: 妊娠, 哺乳, 青光眼治疗

Abstract: In most situations, pregnancy can decrease the intraocular pressure (IOP) of women with pre-existing glaucoma. In managing the pregnant glaucoma patient with medical therapy, we must consider not only the systemic side effects on the mother, but also any potentially harmful effects on the developing fetus. All anti-glaucoma medications are categorized as class C by the Food and Drug Administration, except brimonidine, which belong to class B. Although there are no high quality of researches to prove aitiglaucoma medications causing harmful effects of fetus and newborns, it is better to stop or avoid medications during the first 12 weeks of gestation. In other gestation time, the lowest effective dosage of medication should be considered. Systemic absorption can be reduced by punctal occlusion, eyelid closure, and blotting the excess drops away during administration. In those patients who need surgery, most local anesthetics may be used safely because they have not been shown to be teratogenic in humans. Antifibrotic agents usually used adjunctively in trabeculectomy, however, should be avoided. Glaucoma laser procedures, such as laser peripheral iridotomy and selective laser trabeculoplasty, can be used for pregnant women. (Ophthalmol CHN, 2012, 21: 14-18)

Key words: pregnancy, lactating, glaucoma treatment