眼科 ›› 2023, Vol. 32 ›› Issue (3): 222-227.doi: 10.13281/j.cnki.issn.1004-4469.2023.03.008

• 论著 • 上一篇    下一篇

电热截囊环用于离体猪晶状体截囊的实验研究

卢铭锋 裴雅婧 朱建波 郭彤琳 马科   

  1. 首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科研究所 眼科学与视觉科学北京市重点实验室100730
  • 收稿日期:2023-03-07 出版日期:2023-05-25 发布日期:2023-06-09
  • 通讯作者: 马科,Email:cdmake@163.com E-mail:cdmake@163.com
  • 基金资助:
    国家重点研发计划眼科显微手术机器人系统研制与临床试验(2017YFB1302705)

Experimental study on efficacy of electrothermal capsulorhexis rings assisted anterior capsule membrane circular capsulorhexis of isolated porcine lenses

Lu Mingfeng, Pei Yajing, Zhu Jianbo, Guo Tonglin, Ma Ke   

  1. Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University; Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing 100730, China
  • Received:2023-03-07 Online:2023-05-25 Published:2023-06-09
  • Contact: Ma Ke, Email: cdmake@163.com E-mail:cdmake@163.com
  • Supported by:
    National Key Research and Development Project (2017YFB1302705)

摘要: 目的 观察使用镍铬合金电热截囊环对离体猪晶状体前囊膜的截囊效果。设计 实验研究。研究对象 离体猪眼球50例。方法 50例离体猪眼球随机分为两组:传统连续环形撕囊组(传统组)和电热截囊环辅助截囊组(电热组),每组25例。手术操作在去除角膜后进行,操作全程录像,完成操作后拍照记录前囊口与角巩膜缘。应用计算机软件PotPlayer、Digimizer及MATLAB对图像中的前囊口边缘及角巩膜缘进行标记分析与数学计算,比较两组离体猪眼球前囊膜的截囊效果。主要指标 前囊口的圆度误差值(△Z)、偏心程度(B)、直径(D)、直径误差值(△D)、截囊时间(T)。结果 实验过程中均未发生前囊膜径向撕裂。传统组平均△Z、B、D、△D、T分别为(17.57±6.10) px、(36.99±17.59) px、(5.51±0.95) mm、(0.59±0.49) mm、(26.12±8.82) s;电热组分别为(16.95±7.08) px、(25.54±15.78) px、(5.29±0.50) mm、(0.21±0.23) mm、(43.48±12.31) s。两组的△Z (Z=-0.534,P=0.594)、D (t=1.055,P=0.298)的差异无统计学意义;传统组的B值明显大于电热组(t=2.423,P=0.019);传统组的T值明显短于电热组(t=-5.731, P<0.001);传统组的△D明显大于电热组(Z=-3.218,P=0.001)。结论 电热辅助截囊技术是可行的,在圆度上可获得与连续环形撕囊相似的效果,同时可以获得更好的居中性,撕囊直径更可控,但目前仍会增加手术步骤延长撕囊时间,需进一步改进。(眼科,2023, 32: 222-227)

关键词: 晶状体前囊膜, 白内障超声乳化摘除手术, 连续环形撕囊

Abstract: Objective To explore the efficacy of Nichrome electrothermal capsulorhexis rings assisted anterior capsule membrane circular capsulorhexis of isolated porcine lenses. Design Experimental studies. Participants Fifty solated porcine eyeballs. Methods Solated porcine eyeballs was divided into two groups randomly with 25 cases in each group: continuous curvilinear capsulorhexis group (traditional group) and electrothermal assisted capsulorhexis group (electrothermal group). The surgical procedure will be performed after corneal removal and the whole procedure was videotaped. Anterior capsule holes and corneoscleral limbus were photographed after the operation. PotPlayer, Digimizer and MATLAB were used to perform marker analysis and mathematical calculation of the edge of anterior capsule holes and corneoscleral limbus in the video and image, and then the main indicators were obtained. Main Outcome Measures Circularity (△Z), bias(B), diameter(D), error of diameter(△D), capsulorhexis-time (T). Results There was no radial tearing of the anterior capsule during the experimental process. The average values of the parameters for the traditonal group were: △Z=(17.57±6.10)px, B=(36.99±17.59)px, D=(5.51±0.95)mm, △D=(0.59±0.49)mm, T=(26.12±8.82)s. Those values of the electrothermal group were: △Z=(16.95±7.08)px, B=(25.54±15.78)px, D=(5.29±0.50)mm, △D=(0.21±0.23)mm, T=(43.48±12.31)s. There was no statistically significant difference between the two groups in terms of △Z (Z=-0.534, P=0.594) or D (t=1.055, P=0.298). The B value of the traditional group was significantly greater than that of the electrothermal group (t=2.423, P=0.019). The T value was significantly shorter in the traditional group than in the electrothermal group (t=-5.731, P<0.001). The △D in the traditional group was significantly greater than that in the electrothermal group (Z=-3.218, P=0.001). Conclusion The electrothermal assisted capsulorhexis is feasible and can achieve similar results to continuous curvilinear capsulorhexis in roundness, while achieving better centering, more controllable and ideal diameter of anterior capsule holes. However, it still increasing the surgical steps to extend the time of capsulorhexis. (Ophthalmol CHN, 2023, 32: 222-227)

Key words: anterior lens capsule, phacoemulsification, continuous curvilinear capsulorhexis