关键词: 对比敏感度, 人工晶状体

Abstract: Objective To evaluate visual quality of patients implanted with the extended depth-of-focus IOL Symfony ZXR00 after cataract surgery. Design Prospective nonrandomized controlled comparative study. Participants The study included 42 patients (42 eyes) who had cataract phacoemulsification surgery in the Sixth Medical Center of Chinese PLA Gereral Hospital from June 2021 to January 2022, wherein Symfony ZXR00 IOLs were implanted in 18 cases (18 eyes), and single focus IOLs A1-UV in 24 cases (24 eyes). Methods Visual acuity (VA), defocus curves and contrast sensitivity (CS) were compared 3 months postoperatively between the two groups. Optical interference, spectacle independence and visual satisfaction were also investigated and analyzed. Main Outcome Measures VA (LogMar), CS, defocus curves, optical interference, spectacle independence and visual satisfaction. Results After 3 months, uncorrected distant VA (UDVA)(-0.04±0.08)、uncorrected intermediate VA (UIVA)(-0.03±0.08)、uncorrected near VA (UNVA)(0.28±0.16)、corrected near VA (CNVA)(-0.03±0.05)、distance-corrected intermediate VA (DCIVA)(-0.04±0.07) and distance-corrected near VA (DCNVA)(0.27±0.13)were better in the Symfony ZXR00 group than in the A1-UV group (0.03±0.10, 0.32±0.09, 0.39±0.17, -0.01±0.02, 0.30±0.11, 0.48±0.19), all  P＜0.05. CDVA was similar in the two groups. The Symfony ZXR00 still provided visual acuity greater than 0.3 for a defocus level of -2.50 D. Contrast sensitivity was similar in the two groups at any spatial frequency. The patients in the Symfony group had no serious optical interference, and the spectacle independence rate was 77.8%, which was significantly higher than 0% in the A1-UV group (χ2=28.000, P=0.000). There was no significant difference in the satisfaction rate for distance vision between the two groups. The patient satisfaction rates for intermediate vision in the Symfony group was 100%, which was significantly higher than 20.8% in the A1-UV group (χ2=26.022, P=0.000).For near vision, the satisfaction rates were 77.8% and 0% in the two groups, respectively (χ2=28.000, P=0.000). Conclusion Symfony ZXR00 can provide excellent distance, intermediate and functional near visual acuity, with no significant decline in contrast sensitivity and close to monofocal IOL.   (Ophthalmol CHN, 2022, 31: 355-359)

Key words: contrast sensitivity, intraocular lens