眼科 ›› 2014, Vol. 23 ›› Issue (6): 371-374.doi: 10.13281/j.cnki.issn.1004-4469.2014.06.004

• 论著 • 上一篇    下一篇

激光玻璃体松解术治疗玻璃体Weiss环疗效观察

龚颂建  傅征   

  1. 361001 厦门大学附属厦门眼科中心
  • 收稿日期:2014-05-30 出版日期:2014-11-25 发布日期:2014-12-01
  • 通讯作者: 龚颂建,Email:loyalgg@163.com E-mail:loyalgg@163.com

Efficacy of YAG laser vitreolysis on vitreous Weiss ring

GONG Song-jian, FU Zheng   

  1. Xiamen Eye Center, Xiamen Univercity, Xiamen 361001,China
  • Received:2014-05-30 Online:2014-11-25 Published:2014-12-01
  • Contact: GONG Song-jian, Email: loyalgg@163.com E-mail:loyalgg@163.com

摘要: 目的 探讨Nd:YAG激光玻璃体松解术治疗玻璃体Weiss环的效果。设计 回顾性病例系列。研究对象 以飞蚊症为主诉的、因玻璃体后脱离引起玻璃体漂浮物(Weiss环)的患者192例。方法 选择2004年10月至2013年7月期间在厦门眼科中心接受激光玻璃体松解术治疗玻璃体Weiss环患者192例(218眼),术后随访3~36个月。术前进行视力、眼压、三面镜、裂隙灯照相、眼部B超、部分行眼底全景激光照相、眼底自发荧光检查及荧光素眼底血管造影检查,确定玻璃体Weiss环的位置及大小。Weiss环按直径范围分成:小环<2 mm(119眼),中环2~4 mm(80眼),大环>4 mm(19眼)。选用ZEISS公司生产的VISULAS YAGII或YAGIII激光,单脉冲模式,能量5~10 mJ,将激光瞄准于造成症状的玻璃体漂浮物逐个击散、粉碎、气化。以症状是否完全消失、好转或无效用于评估治疗的效果,并观察是否有其他并发症。主要指标 有效率、好转率、并发症。结果 单个患者单次治疗总能量从56~2136 mJ,平均为(961±354) mJ。 单次治疗时长4~31分钟,平均(18±5.2)分钟。166眼进行1次治疗,35眼2次治疗,17眼3次治疗。症状完全消失者182眼(83.49%),其中小环为94.12%,中环77.50%,大环42.11%;好转者32眼(14.68%),无效者为4眼(1.83%)。未观察到激光直接所致的视力或视野损害、晶状体损伤、眼压升高、视网膜血管损害、色素上皮自发荧光损害等。结论 对于玻璃体Weiss环引起的飞蚊症,在严格选择治疗适应证下,Nd:YAG激光玻璃体松解术治疗是一种相对安全、简便、快捷的手段,尤其对较小漂浮物的患者效果更佳。

关键词: 玻璃体后脱离, Weiss环, 飞蚊症, Nd:YAG激光

Abstract: Objective  To observe the efficacy of YAG laser vitreolysis on vitreous Weiss ring. Design Retrospective case series. Participants 192 patients (218 eyes) complained of floaters because of vitreous floaters (Weiss ring) second to posterior vitreous detachment during the period of October 2004 to July 2013 in Xiamen Eye Center. Methods All the 218 eyes underwent Nd:YAG laser vitreolysis for vitreous Weiss ring and were followed up 3 to 36 months, average 12±3 months. Preoperative visual acuity, intraocular pressure, three mirror examination, slit lamp photography, eye B-mode ultrasound, panoramic laser photography, autofluorescence examination and fundus fluorescein angiography were performed to determine the location and size of Weiss ring in vitreous. According to the size, the Weiss rings were divided into grand central (>4 mm, 19 eyes), central (2~4 mm, 80 eyes), small ring(<2 mm, 119 eyes), and all were treated by Nd:YAG laser (ZEISS, VISULAS YAGII or YAGIII, the single pulse mode, energy 5~10 mJ). The therapeutic effects were observed and evaluated according to the smyptoms completely disappeared, improved, or invalid. Main Outcome Measures  Effective rate, improving rate, complicatins. Results Individual patients with single treatment of total energy from 56 mJ to 2136 mJ, the average was (961 ± 354) mJ. A single treatment time: 4~31 minutes, average (18 ± 5.2) minutes. 166 eyes were treated once, twice in 35 eyes, and 3 times in 17 eyes. Symptoms disappeared completely in 182 eyes (83.49%),in which the effective rate was 94.12 in the small ring, 77.50% in the central ring, and 42.11% in the grand central ring; improved in 32 eyes (14.68%), invalid in 4 eyes (1.83%). No direct laser damages such as induced vision or visual field damage, damage of lens, intraocular pressure increasing, retinal vascular lesions, RPE autofluorescence damage etc were appeared. Conclusion For the Weiss ring caused by vitreous floaters, in strictly selected indications, Nd:YAG laser vitreolysis therapy is a relatively safe and simple, fast means, especially in the small floater.

Key words: posterior detachment of vitreous;Weiss ring, floaters, Nd: YAG laser