Ophthalmology in China

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Change of binocular disparity information in children with amblyopia

LIN Nan1, LU Wei1, SUN A-li1, YAN Li2, ZHANG Ling-ge2, LIU Jun2, WU Dian-peng2   

  1. 1. Beijing Tongren Eye Center, Beijing Key Laboratory of  Ophthalmology and Visual Science, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China; 2. National Engineering Research Center for Healthcare Devices, Zhongshan Guangdong 510500, China
  • Received:2015-05-21 Online:2015-11-25 Published:2015-12-03
  • Contact: LIN Nan, Email: l_nan72@sina.com E-mail: l_nan72@sina.com

Abstract:

Objective To explore the change of binocular disparity information in children with amblyopia. Design Prospective case series. Participants 90 mild, moderate, severe amblyopic children (with 30 cases in each group) with normal eye position. Method The main test method was the computer based visual perceptual test software. Each amblyopic child must take the random dot zero-order disparity, line zero-order disparity, 2nd-order disparity and random dot dynamic 1st-order disparity. Main Outcome Measures The measured value and the pass rate of each disparity. Results In mild, moderate, severe amblyopic children, the proportion of reaching 100"in random dot zero-order disparity was 43.3%, 16.7%, 0% respectively(χ2=25.550,P=0.000); the proportion of reaching 100"in line zero-order disparity was 83.3%,  50.0%, 13.3% respectively (χ2=30.835,P=0.000); the proportion of passing the 2nd-order disparity was 86.7%, 80.0%, 40.0% respectively (χ2=22.144,P=0.000)and the proportion of passing the random dot dynamic 1st-order disparity in a low speed was 80.0%, 50.0%, 13.3% respectively (χ2=27.379,P=0.000). Conclusion The binocular disparity information  in the amblyopic children with normal eye position was abnormal. The more severe the degree of amblyopia, the more serious the binocular disparity abnormality.

Key words: amblyopia, binocular disparity