国际眼科纵览 ›› 2021, Vol. 45 ›› Issue (3): 188-193.doi: 10.3760/cma.j.issn.1673-5803.2021.03.003

• 综述 • 上一篇    下一篇

新生血管性青光眼的治疗

何媛1,权卓娅1,2何蓓蕾1,2张瑞雪1,2   

  1. 1西安医学院第二附属医院眼科 710038;2西安医学院 710021
  • 收稿日期:2020-12-08 出版日期:2021-06-22 发布日期:2021-06-22
  • 通讯作者: 何媛,Email:openji7127@hotmail.com
  • 基金资助:
    国家自然科学基金(81770929、82070964);陕西省教育厅2018年度服务地方科学研究计划(18JC026);陕西省科技厅项目(2019SF-162);陕西省教育厅项目(19JK0758);西安市科技局项目(2019114613YX001SF041-(2))

The research of neovascular glaucoma therapy

He Yuan1, Quan Zhuoya 1,2, He Beilei 1,2, Zhang Ruixue 1,2   

  1. 1Department of Ophthalmology, the Second Affiliated Hospital of Xi'an Medical University, Xi'an 710038, China; 2 Xi'an Medical University, Xi'an 710021, China

  • Received:2020-12-08 Online:2021-06-22 Published:2021-06-22
  • Contact: He Yuan, Email: openji7127@hotmail.com
  • Supported by:
    National Natural Science Foundation of China(81770929, 82070964); Shaanxi Provincial Department of Education in 2018 Serving Local Scientific Research Project Funding (18JC026); Shaanxi Provincial Department of Science and Technology Project (2019SF-162); Shaanxi Provincial Department of Education Project(19JK0758); Xi'an Science and Technology Bureau Project (2019114613YX001SF041-(2))

摘要: 新生血管性青光眼(neovascular glaucoma,NVG)是一种对于药物及手术普遍反应不良的难治性致盲性眼病。早期应用降眼压药物对于延缓疾病进展有效,及时进行全视网膜光凝术控制视网膜缺血性原发病可有效减少新生血管在眼前段的发生率。当发生明显的房角粘连时,可行传统的滤过或引流管植入手术,但结果不尽如人意。目前手术联合抗血管内皮生长因子药物被认为是改善预后的一种新方法,但对眼压的控制结果不良。一些新兴的针对睫状体的手术治疗方式对改善眼压可获得较好效果,然而针对NVG患者哪种治疗选择更好需要进一步研究。(国际眼科纵览,2021, 45:188-193)


关键词: 新生血管性青光眼, 糖尿病视网膜病变, 抗血管内皮生长因子

Abstract: Neovascular glaucoma (NVG) is a kind of refractory blinding eye disease which has poor therapeutic effect to drugs and surgery. Early applications of eye drops to lower the high intraocular pressure levels are effective in prevent any further deterioration of diseases. Panretinal photocoagulation can control the retinal ischemic primary disease and reduce the incidence of neovascularization in the anterior segment.Traditional filtration or shunt surgery is inevitable when peripheral anterior synechia formation and angle closure have occurred, and the results are unsatisfactory. In recent years, surgery combined with anti-vascular endothelial growth factor drugs has been considered as a novel method to improve the prognosis, but was not help to reduce intraocular pressure. Some ciliary body surgical seem to have good benefits on improving intraocular pressure. However, which treatment options are better for NVG patients deserve further investigation and exploration. (Int Rev Ophthalmol, 2021, 45: 188-193)

Key words: neovascular glaucoma, diabetic retinopathy, anti-vascular endothelial growth factor