眼科 ›› 2022, Vol. 31 ›› Issue (3): 213-218.doi: 10.13281/j.cnki.issn.1004-4469.2022.03.009

• 论著 • 上一篇    下一篇

植入TICL对高眼内散光的矫正效果

熊瑛 姚沁楠 万修华   

  1. 首都医科大学附属北京同仁医院 北京同仁眼科中心 北京市眼科研究所 眼科学与视觉科学北京市重点实验室 100730
  • 收稿日期:2022-01-01 出版日期:2022-05-25 发布日期:2022-06-07
  • 通讯作者: 万修华,Email:xiuhuawan@163.com E-mail:xiuhuawan@163.com
  • 基金资助:
    北京市医院管理中心临床医学发展专项经费资助(XMLX202133)

Correction efficacy of Toric implantable collamer lens implantation for high ocular residual astigmatism

Xiong Ying, Yao Qinnan, Wan Xiuhua   

  1. Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Key Laboratory of Ophthalmology and Visual Sciences, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China
  • Received:2022-01-01 Online:2022-05-25 Published:2022-06-07
  • Contact: Wan Xiuhua, Email: xiuhuawan@163.com E-mail:xiuhuawan@163.com
  • Supported by:
    Beijing Hospitals Authority Clinical Medicine Development of Special Funding Support (XMLX202133)

摘要: 目的 比较植入散光型有晶状体眼后房型人工晶状体(Toric implantable collamer lens,TICL)对高眼内散光(high ocular residual astigmatism,HORA)与低眼内散光(low ocular residual astigmatism,LORA)患者的散光矫正效果。设计 回顾性病例系列。研究对象 2020 年7月至12月于北京同仁眼科中心接受V4c型TICL植入术的患者100例(200眼)。方法 眼内散光(ocular residual astigmatism, ORA)是总散光与角膜散光的差值。术前通过主觉验光获得总散光,通过角膜地形图(iTrace视觉功能分析仪)获得角膜散光,利用Alpins提出的矢量分析法计算出总散光与角膜散光的差值获得ORA。再根据ORA大小将术眼分为HORA组(ORA≥1.30 D,94眼)和LORA组(ORA<1.30 D,106眼)。再使用“美国国家标准化组织(American National Standards Institute,ANSI)”推荐使用的标准矢量分析法计算预期矫正散光(intended refractive correction ,IRC)、手术矫正散光(surgically induced refractive correction,SIRC),SIRC与IRC的比值即为矫正率(CR),CR等于1即代表最理想矫正,CR>1表示散光过矫,CR<1则表示散光欠矫。SIRC与IRC之间的差值为误差矢量(EV),EV与IRC之间的比值为误差率(ER),ER为0时代表最理想矫正,ER为1时代表完全未获得矫正。比较两组间上述参数的差异。主要指标 IRC、SIRC、CR、EV、ER。结果 HORA组术后1周时IRC 、SIRC、CR、EV、ER分别为1.52(0.88~2.60)D、1.47(0.83~2.53)D、0.91(0.75~1.16)、0.67(0.39~1.04)D、0.43(0.24~0.90);术后6个月时分别为1.52(0.88~2.60)D、1.37(0.68~2.43)D、0.92(0.69~1.15)、0.7(0.43~1.14)D、0.49(0.28~1.02)。LORA 组术后1周时IRC 、SIRC、CR、EV、ER分别为1.18(0.53~1.70)D、1.1(0.59~1.91)D、1.03(0.66~1.49)、0.57(0.29~1.00)D、0.62(0.31~1.02);术后6个月时分别为1.12(0.53~1.68)D、0.93(0.50~1.67)D、0.91(0.61~1.24)、0.54(0.28~1.07)D、0.61(0.32~1.13)。比较HORA组与LORA 组,术后1周时IRC、SIRC有显著差异(P<0.01、0.01),CR、EV、ER均无统计学差异;术后6个月时,IRC、SIRC和EV有显著性差异(P<0.01,<0.01,0.03),而CR、ER无显著性差异。结论 TICL植入术对于高眼内散光患者的矫正效果与低眼内散光患者无差异。(眼科,2022, 31: 213-218)

关键词: 散光型有晶状体眼后房型人工晶状体, 眼内散光

Abstract: Objective To compare the correction efficacy of Toric implantable collamer lens (TICL) implantation for high ocular residual astigmatism (HORA) with that for low ocular residual astigmatism (LORA). Design Retrospective case series. Participants A total of 200 eyes of 100 patients underwent TICL implantation from July to December 2020 at Beijing Tongren Eye Center. Methods Total astigmatism was obtained by subjective refraction using corneal topography (iTrace visual function analyzer) before surgery. The difference between total astigmatism and corneal astigmatism was calculated by the vector analysis method to obtain intraocular astigmatism (ocular residual astigmatism, ORA). According to the magnitude of ORA, the surgical eyes were divided into HORA group (ORA≥1.30 D, 94 eyes) and LORA group (ORA<1.30 D, 106 eyes). Then, the standard vector analysis method recommended by the American National Standards Institute (ANSI) was used to calculate the intended refractive correction (IRC) and surgically induced refractive correction (SIRC) in both groups. The ratio of SIRC to IRC is the correction ratio (CR). CR equal to 1 represents the most ideal correction, CR>1 indicates overcorrection of astigmatism, and CR<1 indicates undercorrection of astigmatism. The difference between SIRC and IRC is the error vector (EV), and the ratio between EV and IRC is the error rate (ER). When ER is 0, it represents the most ideal correction, and when ER is 1, it represents no correction at all. The differences of the above parameters between the two groups were compared. Main Outcome Measures IRC, SIRC, CR, EV, ER. Results In the HORA group, the IRC, SIRC, CR, EV, ER was 1.52 (0.88~2.60)D, 1.47 (0.83~2.53)D, 0.91 (0.75~1.16), 0.67 (0.39~1.04)D and 0.43 (0.24~0.90) respectively at 1 week after operation; was 1.52 (0.88~2.60)D, 1.37 (0.68~2.43)D, 0.92 (0.69~1.15) , 0.7 (0.43~1.14)D and 0.49 (0.28~1.02) respectively at 6 months after surgery. In the LORA group, the IRC, SIRC, CR, EV, ER was 1.18 (0.53~1.70)D, 1.1 (0.59~1.91)D, 1.03 (0.66~1.49), 0.57 (0.29~1.00)D and 0.62 (0.31~1.02) respectively at 1 week after operation; was 1.12(0.53~1.68)D, 0.93(0.50~1.67)D, 0.91(0.61~1.24), 0.54(0.28~1.07)D and 0.61(0.32~1.13) respectively at 6 months after surgery. Comparing the HORA group with the LORA group, there were significant differences in IRC and SIKC (P<0.01, 0.01), but no significant difference in CR, EV and ER at 1 week after operation. There were significant differences in IRC, SIRC and EV at 6 months after operation(P<0.01, <0.01, 0.03), but no significant difference in CR and ER. Conclusion Toric Implantable collamer lens (TICL) have the same good correction effect for astigmatism in the HORA group as in the LORA group. (Ophthalmol CHN, 2022, 31: 213-218)

Key words: Toric implantable collamer lens, ocular residual astigmatism