Abstract:

Objective To observe the efficacy of Zhenqi eye drop steam massage on dry eye patients. Design A perspective, randomized, opening, positive eye drop parallel controlled clinical study. Participants All the 96 patients were observed in Tongren hospital from 2013 to 2015 in out patients, the mean age was 60.95±12.22 year old. Methods Ninety-six patients with dry eye were randomly divided into two groups, the testing group and the control group, with 1 by 1 ratio. The testing group and the control group were both given vitrobolik eye drops, 4 times a day. In addition, the testing group were given Zhenqi eye drop stream massage, 20 min per day, and the control group were given Zhenqi eye drop 4 times a day without steam massage. All the patients were observed for 4 weeks for the improvement of symptoms and clinical signs. Main Outcome Measures The clinical effectiveness ratio, total scores of symptoms, Schimer I test(SIt), tear break-up time(BUT), cornea fluororencein staining. Results There were no significant difference between testing group and control groups in total scores of symptoms, SIt, tear BUT, cornea fleuororencein staining before treatment. The clinical effectiveness ratio was 81.25% in the testing group, significantly higher than 62.50% (P=0.041) in the control group after 4-week treatment. And the tear BUT improved significantly in testing group 7.53±3.78 s than in the control group(P=0.041). The total score of symptom was 1.92±1.99 in the testing group and 2.32±2.30 in the control group(P=0.031). Conclusion Dry eye can be effectively treated using Zhenqi eye drop steam massage. The efficacy of Zhenqi eye drop steam massage was better than vitrobolik eye drop. （Ophthalmol CHN, 2016, 25： 347－350）

Key words: dry eye, herbs stream massage