Abstract: 【Abstract】 Objective To evaluate the feasibility and value of screening for fundus diseases with digital nonmydriatic fundus camera in 50-year-old or elder community citizens. Design cross-sectional survey. Participants 3742 residents aged 50-year-old or elder by telephone notices and posters recruitment from Wanshoulu blocks and Tiancun blocks, Haidian district, Beijing. Methods Fundus photos were taken with digital nonmydriatic fundus camera and slit-lamp microscopic examination of the anterior segment of all subjects was performed after visual acuity examination. Cases screened as macular diseases with photos were undergone optical coherence tomography (OCT) examination. Main Outcome Measures Composition ratios of fundus diseases. Results Among all the screened 3742 subjects, 2914 subjects acquired qualified fundus photos, 13 fundus diseases were screened, including retinal arteriosclerosis (37.1%), suspect glaucoma (9.27%), aged-related macular degeneration (6.11%), diabetic retinopathy (2.23%), asteroid hyalosis (0.89%), myelinated nerve fibers (0.58%), retinal vasculitis (0.51%), epiretinal membrane of macula (1.30%), suspect macular hole (1.20%), retinal vein occlusion (0.14%), optic atrophy (0.17%), optic disc macroaneurysm (0.03%), other fundus abnormality (0.32%). Images of macular degeneration, epi-macular membrane and macular hole were compared with OCT scanning, the result consistent rate of the two methods is 86.90%. 828 subjects (22.13%) are excluded because their fundus images were unclear and couldn’t be analyzed. The rate un-evaluation of fundus images was increasing with aging. Conclusion It is an objective and feasible screening method for fundus disease with digital nonmydriatic fundus camera in most 50-year-old or elder subjects. (Ophthalmol CHN, 2013, 22: 230-233)

Key words: digital fundus photography, fundus disease, screening