Ophthalmology in China

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Application of intraocular fluid testing in the diagnosis of uveitis

Yang Peizeng, Xu Jing, Su Guannan   

  1. Department of Ophthalmology, the First Affiliated Hospital of Chongqing Medical University, Chongqing Institute of Ophthalmology, Chongqing Key Laboratory of Ophthalmology, Chongqing 400016, China
  • Received:2020-03-06 Online:2020-05-25 Published:2020-06-05
  • Contact: Yang Peizeng, Email: peizengycmu@126.com E-mail:peizengycmu@126.com
  • Supported by:
    Chongqing Key Laboratory of Ophthalmology and Discipline Construction Project (cstc2008CA5003); Chongqing science and technology research and development base capacity improvement project (cstc2014pt-sy10002); Social Undertakings and People's Livelihood Security Science and Technology Innovation Special Key Projects of Chongqing Science And Technology Commission (cstc2017shmsA130073); Chongqing talent Outstanding scientist (2019)

Abstract: Intraocular fluid testing is a laboratory examination used in the diagnosis of certain intraocular inflammatory diseases or in the investigation of relevant factors associated uveitis. The specific examinations and their indications of intraocular fluid testing as well as explanation of the test results obtained are described in detail in this paper. The abused employment of intraocular fluid testing and misunderstanding of these results become a serious problem right now in clinical practice. In general, the diagnosis of uveitis is a clinical one and principally based on history taking, meticulous clinical examination and, if necessary, relevant auxiliary examinations. Intraocular fluid testing is useful only in the diagnosis of endophthalmitis, masquerade syndrome associated with malignancies, ocular toxoplasmosis and ocular toxocariasis. Extensive and indiscriminate intraocular fluid testing used in searching for underlying origins or causes of uveitis is a wasteful practice, frequently leading to misdiagnosis and mistreatment, and sometime puts patients at risk to development of intraocular infection.

Key words: uveitis, intraocular fluids analysis, diagnosis