关键词:  , 眼眶；结膜；淋巴瘤；磁共振成像

Abstract: Objective To deepen understanding the cognition of MRI features of conjunctival lymphoma. Design Retrospective cases series. Participants Twenty-one patients with conjunctival lymphoma first visiting the ophthalmology department of Beijing Tongren Hospital. Methods The clinical, MRI and histological features of 21 cases were reviewed. Main Outcome Measures The original locations, invasive extent， and MRI features of the tumor. Results In the 21 cases (25 eyes), the lesion located in the superior palpebrae conjunctiva in 4 eyes, the inferior palpebrae conjunctiva in 7 eyes, and both palpebrae conjunctiva in 14 eyes, respectively. Most of the lesions were limited to conjunctiva or eyelids (19 eyes, 76%) and others invaded the orbits (6 eyes, 24%; 2 eyes involving intraconal compartment, extraocular muscles and lacrimal gland; 3 eyes involving superior ocular muscles, 1 eye involving tenon follicle and optic nerve). There were well-defined margin in 15 eyes and ill-defined margin in 10 eyes. The lesions in 17 eyes circled the eye ball and in the other 8 eyes just located in the anterior eye segment. All the cases showed isointense on T1WI compared with ocular muscles. 18 eyes showed isointense and 7 eyes showed mild hyperintense on T2WI. Moreover, the signals were homogeneous in 18 eyes and heterogeneous in 7 eyes. 13 cases (15 eyes) had contrast-enhanced MRI. After injection of the Gd-DTPA, they showed mild to moderate enhancement. In 7 cases (8 eyes) for dynamic contrast-enhanced, 6 eyes showed plateau pattern and 2 eyes showed washout pattern in time-intensity curve. Conclusion Conjunctival lymphoma shows homogeneous isotense on T1WI and T2WI with mild to moderate enhancement in contrast-enhanced MRI， and plateau pattern in time-intensity curve. (Ophthalmol CHN, 2013, 22: 320-323)

Key words: orbit, conjunctiva, lymphoma, magnetic resonance imaging