Ophthalmology in China ›› 2022, Vol. 31 ›› Issue (5): 330-333.doi: 10.13281/j.cnki.issn.1004-4469.2022.05.002

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Extracellular deposits associated with age-related maculopathy: basal laminar deposit

Huang Houbin   

  1. Senior Department of Ophthalmology, PLA General Hospital, Beijing 100853, China; Department of Ophthalmology, Hainan Hospital of PLA General Hospital, Sanya 572013, China; The Second School of Clinical Medicine, Southern Medical University, Guangzhou 510280, China
  • Received:2022-05-10 Online:2022-09-25 Published:2022-09-26
  • Contact: Huang Houbin, Email: 536273642@qq.com
  • Supported by:
    High and New Technology Project of Hainan Key Research and Development Plan (ZDYF2020031); Special Scientific Research Project of the Logistic Support Department of the Chinese Military Committee(19BJZ39)

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Abstract: With age, many deposits predominantly lipoprotein-derived debris can accumulated in the basal lamina of basement membrane of retinal pigment epithelium (RPE) besides between the basal lamina of basement membrane of RPE and the inner collagenous layer of Bruch's membrane. This kind of deposit is called basal laminar deposit, while thickens the basal lamina of RPE. Basal laminar deposit is difficult to be detected clinically, while appears as a high reflex line by OCT between outer retina and sub-RPE space in the some case of RPE atrophy. (Ophthalmol CHN, 2022, 31: 330-333)

Key words: lipoprotein-derived debris, basal laminar deposit, age-related macular degeneration