Abstract: Rhythm is one of the essential basic features of nature, which enables organisms to better adapt to the environment and maintain the coordination of life processes through the appropriate phase relationship, seasonal changes, cloudy and sunny days, and night alternation are all rhythms. Biological rhythm is a regular change in the phenomenon of life, which plays an important role in the process of organ development and physiological regulation. In the change of external rhythm, light plays an important role, and there is also a rhythm in the change of light itself. The eye is the most important organ of natural light perception, and external and internal rhythms regulate its development and internal structure. Light signals are projected to the suprachiasmatic nucleus (SCN), the "master biological clock", by the intrinsically photosensitive retinal ganglion cells of the eye, resulting in daily rhythmic photo synchronization. When abnormal light exposure leads to biorhythmic dysregulation, the body may alter the balance of developmental hormones such as dopamine and melatonin by regulating the synchronization between the retinal biological clock and the SCN, disrupting eye growth and development and producing abnormal refractive status. In this paper, we analyze the effects of biorhythms on refractive development and myopia in recent studies to provide new ideas for the prevention and treatment of myopia. (Ophthalmol CHN, 2023, 32: 84-88)

Key words: biological rhythm, refractive development, myopia, light