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    Research team teaching method in ophthalmological practice
    FU Jing
    Ophthalmology in China    2015, 24 (4): 275-277.   DOI: 10. 13281/j. cnki. issn.1004-4469. 2015. 04. 014
    Abstract914)            Save

    Research team teaching in ophthalmology is a task-oriented teaching method of ophthalmology, aiming to improve the research capacity of an academic research team. Every team member is encouraged to participate, and his role is rotated between teaching and learning. The teaching content is settled around the research project of ophthalmology, including experimental method, relevant theoretical knowledge, and project progression and quality control. Several forms of teaching-learning methods are included, such as one to one or one to many training, group meeting, reading club, and salon. Through those learning process, team members can develop their abilities needed for specific project, including the innovation ability, analyzing and problem-solving ability, thereby enhance the research efficiency and core competitiveness of the ophthalmological team. (Ophthalmol CHN, 2015, 24: 275-277)

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    Comparision of the clinical efficacy of vitrectomy combined with cyclophotocoagulation and trans-scleral cyclophotocoagulation to treat secondary glaucoma
    ZHOU Dan, HE Lei, PANG Xiu-qin
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.05.011
    Inhibition of Akt activity enhances the sensitivity of retinoblastoma SO-Rb50 cell line to carboplatin in vitro
    ZHANG Hao1, WANG Yi-chen2, LI Bin2, YANG Su-hong1, GONG Yue-qiu1
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2015.06.014
    Diagnosis and management of fungal infected optic neuritis
    TAN Shao-ying, XU Quan-gang, WEI Shi-hui, ZHAO Jie
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.03.012
    Strategy of management and implementation of international medical aiding program-taking Bright Jounery Program in Ghana as an example
    WANG Jia-wei1, WEI Xian-jing1, ZHOU Zi-xiao2, CHEN Jia-yong3, LIANG Xiao-song1, LIU Wei-ci1
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.03.018
    Cultivation of clinical and scientific research ability for master degree candidates whose major in the ocular tumor and orbital disease
    MA Jian-min, LIU Xiao, MA Ke
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.05.017
    Clinical observation of changes in posterior corneal surface after transepithelial photorefractive keratectomy
    SU Yan, HOU Jie, ZHENG Xiu-yun, LEI Yu-lin
    Ophthalmology in China    2014, 23 (3): 161-164.   DOI: 10.13281/j.cnki.issn.1004-4469.2014.03.005
    Abstract1754)            Save
    Objective To observe the changes of posterior corneal surface after transepithelial photorefractive keratectomy (T-PRK) and epipolis laser in situ keratomileusis (Epi-LASIK) for myopia. Design Prospective comparetive case series. Participants 134 eyes of 68 miopia patients were divided into T-PRK group (81 eyes) and Epi-LASIK group (53 eyes). Methods Posterior corneal elevation and Q-value were analyzed using pentacam before and 1 week, 1, 3 and 6 months after operation,respectively. Main Outcome Measures Posterior coneal elevation and Q-value. Results In the T-PRK group, at 1st and 6th month after surgery and in the Epi-LASIK group at 6th month after surgery, the posterior corneal elevation have a statistically significant backward displacement(all P<0.05). No statistically significant difference was found in the postoperative corneal Q-value in both groups before and after surgery(all P>0.05). There was also no statistically significant difference of postoperative corneal surface elevation and Q-value between the two groups (all P>0.05). Conclusion The posterior corneal elevation showing a backward displacement after T-PRK for myopia,while posterior corneal asphericity has no changed.
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    Practice of problem-based learning method in strabismus course for residents
    HONG Jie, FU Jing
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.02.020
    Water drinking test influences intraocular pressure, axial length and choroid thickness in normal young adults
    ZHANG Hui,HONG Jie, HUO Yan-jiao, WANG Huai-zhou, WANG Ning-li.
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.01.008
    Clinical diagnosis, treatment and efficacy of 97 cases of pediatric orbital cellulitis
    FAN Yun-wei, WU Qian, YU Gang, CAO Wen-hong, WANG Yuan, LIU Wen
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2015.06.012
    Take full advantage of clinical medical images in ophthalmic anatomy teaching
    PENG Xiao-yan, XU Zhang-xing
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2015.05.017
    The effect of tear film function on the activity of primary pterygium 
    GAO Yang1, ZHOU Jin2, SUN Xiao-fang3.
    Ophthalmology in China    2015, 24 (1): 44-46.   DOI: 10.13281/j.cnki.issn.1004-4469.2015.01.012
    Abstract861)            Save
    Objective To explore the effect of functional tear film on constitutional pterygium. Design Prospective comparative case series. Participants 53 cases of monocular patients with primary pterygium in Nanlang Hospital of Zhongshan City from August 2012 to February 2013. Method  14 pterygium patients with stationary phase and 39 patients with active phase were included in this study. All patients were examined  with Schirmer test, tear film break-up time (BUT) and conjunctival impression cytology for golblet cell count. Logistic regression was used to analyze associated factors and ptetygium activity.  Main Outcome Measures  Schirmer test, BUT and conjunctival golblet cell density. Results The result of Schirmer test in stationary phase and active phase was (9.43±2.28) mm and (8.67±2.14) mm, respectively (P=0.267). While the result of BUT in stationary phase and active phase was (8.79±1.97)s and (5.05±2.14)s, respectively (P=0.000). The mean globlet cell density (numbers/10 fields) in conjunctival impression specimens in stationary phase and active phase was (38.79±2.83) and (32.74±3.30), respectively (P=0.000). The logistic regression analysis showed that only BUT could affect the activity of ptetygium. Conclusions The active state of pterygium is associated with ocular surface status of patients. The patients of pterygiumms in active phase suffer poor tear film compared with patients in stationary phase. (Ophthalmol CHN, 2015, 24: 44-46)
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    Effect of ultraviolet irradiation on the stability of tear film and corneal tissue of rats
    LIU Wei-yang,WU Xin-na, HUANG Yan,XIE Pin, CAI Xiang-heng, YAN Zhi-peng
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.02.007
    Study on human visual fatigue induced by watching linear polarized liquid crystal display and circular polarized liquid crystal display with eye tracker 
    ZHANG Li1, XU Liang1, ZHANG Yun-hong2, LI Jian-jun1.
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.01.013
    Second stage fixed to the ciliary sulcus of common capsular tension ring for moderate and severe lens subluxation
    CHEN Zhi-min1, ZHANG Wu-lin1, WU Wei-jing2, LIN Zhi-hui1, YANG Rong1.
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.02.002
    Retinal vessel oxygen saturation in Chinese healthy individuals
    YANG Jing-yan, YOU Bing, WANG Qian, ZENG Si-yan, WEI Wen-bin
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.05.013
    Clinical characteristics and causes of laser-induced maculopathy
    CHEN Yan-yun, LI Ji-peng, LU Ning
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.03.014
    Two novel mutations in Best vitelliform macular dystrophy GONG
    GONG Li-xue, GU Hong, LIU Shou-bin, LIU Ning-pu, MA Kai
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.03.011
    Application of Accommodation Analyzer-1 on assessment of visual fatigue induced by watching 3D video
    ZHANG Li, XU Liang, WANG Xiao-bing, ZHAO Shi-qiang, LI Jian-jun
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2015.06.010
    Application practice and exploration of workshop teaching method in ophthalmic surgical skills training in postgraduate students
    LI Dong-mei, ZHOU Jin-qiong
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.02.021
    Ocular surface microbial distribution and clinical analysis of blepharitis
    GAO Rui, SUN Xu-guang, WANG Zhi-qun, ZHANG Yang
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.02.012
    The effects of recessive placement of spherical headed silicone tube for chronic dacryocystitis
    LU Jun-Hua, PAN Xue-Fei, ZHAO Mao-Zhu
    Ophthalmology in China    2014, 23 (2): 126-129.   DOI: 10.13281/j.cnki.issn.1004-4469.2014.02.013
    Abstract830)            Save
    Objective To observe the clinical effects of the recessive placement of spherical headed silicone tube on treatment of chronic dacryocystitis. Design Retrospective case series. Participants 65 patients ( 67 eyes) with chronic dacryocystitis. Methods All the participants were accepted the operations of the recessive placement of spherical headed silicone tube. Using the method of probing of lacrimal passage, the traction line was sent into the inferior nasal meatus using the 8-pin, after the expansion of nasal tube using the expansion rope, the ball head silicone tube was tracted retrogradely guaided by the traction line and implanted. Then the lacrimal passages were washed with plus gentamicin and dexamethasone mixture and saline irrigation after the operation once a day in one week, after 1 week once a week, for 3 months, and the tube was removed three to six months after placing. The lacrimal passages were washed with antibiotic and hormone (about 4 times), the tube was injected with TobraDex after the tube was removed. The symptoms were observed in the following 3 months to 2 years.  Main Outcome Measures The symptom of epiphora and pus, the situation of lacrimal duct. Results After the tube planting,  the lacrimal duct system of totally 65 patients (67 eyes) were able to be irrigated successfully. 49 eyes(73.13%) were cured after the removal of silicone tube during the follow-up period, and the symptom of epiphora and pus disappeared, there were no serious intra- and post-operative complications. Conclusion Recessive placement of spherical headed silicone tube is an effective method for the most chronic dacryocystitis. (Ophthalmol CHN, 2014, 23: 126-129)
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    Six-months result of minimally invasive phacotrabeculectomy in the treatment of patients with acute angle-closure glaucoma and coexisting cataract 
    HOU Xu, HU Dan, CUI Zhi-li, ZHOU Jian, CAI Li, WANG Yu-sheng.
    Ophthalmology in China    2015, 24 (1): 31-35.   DOI: 10.13281/j.cnki.issn.1004-4469.2015.01.009
    Abstract1273)            Save
    【Abstract】 Objective To study the effect of the application of minimally invasive phacotrabeculectomy in patients with unresponsive acute angle-closure glaucoma. Design Retrospective case series. Participants 15 cases(15 eyes)with acute angle-closure glaucoma and coexisting cataract in Xijing Hospital between March 2011 to March 2013. Methods Preoperative topical corticosteroids, mannitol, methazolamide and paracentesis were applied to reduce intraocular pressure (IOP). A standard phacoemulsification was performed, followed by minimally invasive trabeculectomy with a fornix-based conjunctival flap (5 mm) and small sclera flap (3 mm). Main Outcome Measures Visual acuity, IOP, anterior chamber depth, inflammatory reaction, and bleb-related complications. Results Pre-operative average IOP was (53.13±8.82) mmHg. One week after surgery the visual acuity of all patients was improved significantly, and the IOP was (13.41 ± 3.42) mmHg. 3 and 6 months after surgery IOP was (14.65±4.21) and (15.35±5.48) mmHg, respectively. Inflammation in the anterior chamber subsided postoperatively at one week, inflammatory exudate was almost absorbed, and anterior chamber depth was significantly deeper at two weeks, with an average of (2.72 ± 0.38) mm. All 15 eyes had diffuse blebs or elevated blebs with microcystic changes in the conjunctiva between 3 months to 6 months postoperatively. Postoperative vision acuity was (0.92±0.48) at 6 months. No serious adverse complications were encountered during follow-up. Conclusion Minimally invasive trabeculectomy could reduce tissue injury and improve the safety of surgery, which is an effective method when combined with phacoemulsification in the treatment of patients with unresponsive acute angle-closure glaucoma and coexisting cataract. (Ophthalmol CHN, 2015, 24: 31-34)
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    Application of problem-based study combined with case-based study teaching mode in the education of postgraduate students
    WANG Jun, CAO Ying-xue, XU Liang
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.05.018
    Irritant test of dihydroartemisinin ointment in rabbit eyes
    WANG Zhi-qun, ZHANG Yang, QU Jing-hao, ZHANG Xiao-yu, SUN Xu-guang
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.02.011
    The effect of double incision joint nuclear extraction with two-dialer in extracapsular cataract extraction procedure for restoring-vision cataract projects
    YANG Li-dong, YANG Yun-dong, XU Shen
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.02.003
    Clinical analysis of fungal keratitis in Xishuangbanna Autonomous Prefecture, Yunnan Province in 2004-2014
    ZHAO Nan-nan1, WANG Li-tao2, JIN Jing2, ZHOU Qing2, LUO Ping2.
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.01.013
    Curative effects of lacrimal duct drill combined with lacrimal duct intubation on chronic dacryocystitis
    LIN Zai-xiong, WU Jiang, LI Ke, CHEN Zhi, LI Meng-en
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.06.004
    Protective effects of pentazocine on retinal Müller cells under high-glucose conditions
    CUI Le-le, WANG Yun-song, SHAN Ming-hua, ZHOU Yun-tao, TIAN Wei
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.03.004
    Investigation and analysis on the participant status of medical staff from primary hospital in a tele-ophthalmology project
    MA Yi1, 2, LI Jian-jun2, LIU Li-juan2, WANG Shuang2, LU Qing-jun2,3, XU Liang2, CHEN Juan1
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2015.06.017
    Clinical characteristics and prognosis of cytomegalovirus retinitis with acquired immune deficiency syndrome  without anticytomegalovirus therapy
    SUN Hui-yu, MAO Fei-fei, LI Dan, WANG Sheng-nan, LIU Yue-hong, XU Xue-jing, LIU Bin-bin, DONG Yu
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.03.011
    Etiology and clinical characteristics of infantile cataract combined with vitreous abnormities
    MA Yan, LU Hai
    Ophthalmology in China    2015, 24 (2): 103-107.   DOI: 10.13281/j.cnki.issn.1004-4469.2015.02.008
    Abstract772)            Save
    Objective To investigate clinical characteristics and etiology of infantile cataract combined with vitreous abnormalities. Design Retrospective and non-controlled case series. Participants From January 2013 to July 2014 at Beijing Tongren Eye Center eighty-four children (114 eyes) aged 3-year old or younger who were diagnosed as cataract and detected vitreous abnormality by ophthalmic color Doppler flow imaging (CDFI) ultrasound were enrolled. Methods Charts of these patients were reviewed. Age, chief complaints, signs, CDFI examination and suggested diagnosis, proven diagnosis, past history, family history, and pregnancy history of their mothers were recorded. Etiology and clinical characteristics were analyzed. Main Outcome Measures Age, symptoms, course, signs, CDFI manifestations and suggested diagnosis, proven diagnosis. Results Age at presentation varied from 0 to15 months (2.7±3.0 months). Age at diagnosis was 2~20 months (7.8±4.2 months). Abnormalities were noticed by parents in 81 cases (96.4%) and detected by eye examinations in 3 cases (3.6%). The first noticed symptoms were leukocoria in 39 cases (46.4%), unable to follow objects in 16 cases (19.0%), strabismus in 10 cases (11.9%), and binocular asymmetry in 7 cases (8.3%). The cataract was complete type in 75 eyes (65.8%), posterior polar type in 38 eyes (33.3%), and membranous type in 1 eye (0.9%). They could complicate with nystagmus, strabismus, microphthalmia, shallow anterior chamber, secondary glaucoma, persistent pupillary membrane, tractional retinal detachment and coloboma of choroid. CDFI suggested diagnosis included persistent hyperplastic primary vitreous (PHPV) in 111 eyes (97.4%), retinal detachment in 3 eyes (2.6%). Confirmed diagnosis after surgery included PHPV in 76 eyes (66.7%), family exudative vitreoretinopathy (FEVR) in 14 eyes (12.3%) and congenital cataract in 24 eyes (21.0%). CDFI suggested diagnosis and post-operative confirmed diagnosis were consistent in 69.3% cases. Conclusion Patients who were diagnosed as infantile cataract presumptively with abnormal vitreous were mostly at large month-old and mostly noticed as leukocoria by their parents, which could complicate with a variety of ocular abnormality. Pre-operative CDFI examination could detect vitreous and retinal disorders. (Ophthalmol CHN, 2015, 24: 103-107)
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    Clinical observation of optic disc parameters and pRNFL thickness in tuberculum sellae meningiomas
    WANG Li-na, YANG Liu, QU Yuan-zhen
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2015.06.016
    Efficacy of scleral buckling procedures for longstanding rhegmatogenous retinal detachment
    SHEN Zhi-jun, DUAN An-li
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2015.06.013
    Effects of a broad-spectrum mechanosensitive ion channels inhibitor ruthenium red on intraocular pressure
    FANG Jing-wang1, TIAN Li-ping2, LIU Ya-ni1, WU Shen3, ZHANG Jing-xue3, XIN Chen3, WANG Ning-li3, ZHU Wei1
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2019.03.009
    Clinical features of 18 cases of ethambutol-induced optic neuropathy
    CAO Shan-shan1, PENG Chun-xia1, LI Xiao-ming2, ZHANG Xiao-hui3, WEI Shi-hui1
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2016.02.013
    Refractive changes after pharmacologic resolution of macular edema induced by retinal vein occlusion 
    WU Xi-shi,ZHENG Bin,LIN Li,SHEN Li-jun.
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.01.011
    Clinical characteristics and treatment effect in patients with facial rosacea combined ocular damage
    CHEN Ying-Xin, GAO Ming-Hong
    Ophthalmology in China    2014, 23 (2): 121-125.   DOI: 10.13281/j.cnki.issn.2014.02.012
    Abstract1183)            Save
    Objective To investigate the clinical characteristics and treatment of facial rosacea with ocular damage. Design Retrospective case series. Participants Sixteen cases of facial rosacea with ocular damagewere enrolled from January 2010 to December 2012. The age range at presentation was between 16 and 56 years. Methods 16 cases of medical records were followed up for 12 months. In addition to gross inspecting rosacea lesions of the eyes and face, slitlamp and microscope were used to detect the subtle changes in the face and eyes, particular vascular abnormalities. Tests of tear production and tear breakup time (BUT) were performed in 12 patients with ocular dry sensation. Mites were checked on face and nasal skin, and microbiological examination and culture were performed on the palpebrals. Minocycline hydrochloride was used orally 50 mg, twice one day for 3 to 6 months. Topical corticosteroids (loteprednol suspension eye drop) and antibiotic (levofloxacin) were used 3 times one day until two weeks after ocular changes were negative. Main Outcome Measures Skin changes, ocular changes, Schirmer test and tear film BUT. Results Clinical features: common signs of facial skin showed erythema vasodilation hyperplasia in 16 patients (100%), conjunctival hyperemia and conjunctival vasodilation deformation or hyperplasia in 16 patients(100%), 14 cases (87.5%) of blepharoconjunctivitis and 12 cases (75%) of dry eye. Less common signs were including 4 cases (25%) of inferior corneal tongue and tree-like pannus, 6 cases (37.5%) of facial rhinophyma, 4 cases (25%) of corneal ulcers, 4 cases (25%) of episcleritis and two cases (12.5%) of iridocyclitis. After the medication treatment, skin and eye lesions of all the participants were significantly improved (100%). It showed that erythema of facial and nasal skin, and corneal pannus was subsided, corneal infiltrates and conjunctival hyperemia disappeared. Conclusion Atypical ocular clinical manifestations were often difficult to identify, vascular changes was the basis sign, facial vascular changes were often combined for diagnosis. And it was very effective to use minocycline hydrochloride combined with corticosteroid for facial rosacea with ocular damage. (Ophthalmol CHN, 2014, 23: 121-125)
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    Reproducibility of parafoveal choroidal vessel layer thickness measurements with enhanced depth imaging by spectral-domain optical coherence tomography 
    ZHAO Jing, WANG Ya-xing, ZHANG Qi, LI Jian-jun, XU Liang.
    Ophthalmology in China    DOI: 10. 13281/j. cnki. issn.1004-4469. 2016. 01. 011
    Surgical approach and long-term outcome of uveal neurogenic tumor
    HUANG Yao, XU Xiao-lin, LI Bin, WEI Wen-bin
    Ophthalmology in China    DOI: 10.13281/j.cnki.issn.1004-4469.2017.03.010